What Are The Real Symptoms Of A Heart Attack? They cause your diaphragm to become smaller or larger so your lungs can inhale and exhale air. What causes irritation of the phrenic nerve? It is often caused by nerve, spinal cord, or brain irritation or damage. I also have a lot of indigestion and burping and chest discomfort. It should not be used for diagnosis or as a substitute for health care by your physician. Difficulty swallowing (especially pills and The Foundation for Peripheral Neuropathy. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. I have heard about this Doctor Kaufman at UCLA but I have to have several tests before I can even be seen by Him. Peripheral neuropathy is a disease characterized by pain or loss of function in the Acid Reflux/Heartburn (because of LOW STOMACH ACID !) Diaphragm and diaphragmatic pleura (thin tissue covering the upper part of your diaphragm). It sends signals that cause your diaphragm to expand and contract. Certain infections can cause neuropathy, such as HIV and Lyme disease. Some people even notice that their ribs pop out and need chiropractic manipulation. This site complies with the HONcode standard for trustworthy health information: verify here. information submitted for this request. it is a sniff test, a pulmonary function test and an emg. hiccups, cough, dyspnea, pleural effusion and thoracic pain. 2021;48(1):1-4. doi:10.1186/s43166-020-00051-0, Goff RP, Spencer JH, Iaizzo PA. MRI reconstructions of human phrenic nerve anatomy and computational modeling of cryoballoon ablative therapy. I am hoping they can figure this out and something can be done to help my situation. 1. Scand J Pain. (2015). Fortunately, you can usually live a normal life even with one-sided diaphragmatic paralysis. That led me to a Dr. Kauffman from New Jersey who also practices at UCLA with another doctor, and is performing phrenic nerve surgery on patients with phrenic nerve damage. In MS you can experience acute neuropathic pain and chronic neuropathic pain. It sends signals to your brain, which allows you to breathe without thinking. The good news? As Health n Joy wrote, since the symptoms of phrenic nerve damage aren't some regular symptoms which could be noticed by doing tests or so, the doctor is just going to talk to you and ask you question about your daily activities and how you react to them in order to conclude whether or not do you have a phrenic nerve damage. It passes motor information to the diaphragm and receives sensory information from it. I have researched on my own and found out that the Phrenic nerve goes through the C4 area where I was injured. If you overexert your diaphragm during exercise, it may start to spasm. I can do my own work since I am a touch for health practitioner. It comes in any and all shapes and sizes and symptoms, Loeser says. WebAs peripheral neuropathy can be a very painful and troublesome problem that may only partly be relieved by standard treatments, you may be tempted to try other therapies. Since stroke 3 years ago??? 2015;8(4):1314. doi:10.4022/jafib.1314, By Lynne Eldridge, MD WebA phrenic nerve disorder on one side can especially cause breathing difficulty in people with obesity, heart disease, or lung disorders. The diaphragm is located between the upper abdomen and the chest. An expert surgeon will join the two ends of the phrenic nerve. Health conditions that can cause peripheral neuropathy include: In a number of cases, no cause can be identified (idiopathic). He is currently working on contacting Dr. Kauffman again to arrange a video conference with my husband and myself, to see if my husband is a good candidate for the surgery. Some children undergoing surgery to treat heart defects also suffer damage to the phrenic nerve. Vagus nerve and phrenic nerve irritation are known causes of chronic hiccups. You will feel short of breath, especially when lying down. The right phrenic nerve descends along the inner aspect of the lung and passes just lateral to the right atrium and right ventricle of the heart. Accessed March 26, 2019. Slowly breathe in through your nose. Swanson JW (expert opinion). In the chest, it passes through the mediastinum, a space between the lungs that also contains the heart, blood vessels, esophagus (food pipe), and other nerves. 3) Set personal goals and celebrate your successes, even if theyre small. Separate groups of nerve fibres are He has 56% lung function currently. WebSome days I feel like my body is covered in napalm. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Phrenic nerve palsy Symptoms. These are the most common symptoms of the phrenic nerve palsy: Dyspnea (shortness of breath) Orthopnea (dyspnea that is relieved by assuming the orthostatic position) Hiccups (also caused by the irritation of the respective phrenic nerve) Diaphragm paralysis (the patient is no longer able to breathe on his/her own) Signals from the nerve (which can be voluntary or involuntary) cause the diaphragm to contract and flatten during inspiration, drawing air into the lungs. What Is Thyroidectomy And Why Is It Performed? When the spasm is chronic, it might be due to exercise-induced bronchospasm, and you may also experience: A diaphragm flutter is a rare condition that can be misdiagnosed as a spasm. The diagnosis of phrenic nerve injury requires high suspicion due to nonspecific signs and symptoms including unexplained shortness of breath, recurrent pneumonia, anxiety, insomnia, morning headache, excessive daytime somnolence, orthopnea, fatigue, and difficulty weaning from mechanical ventilation. Connects to the C4 and C5 vertebral levels in your neck, below the C3 vertebra. With phrenic nerve irritation, you might also experience: hiccupping shortness of breath when lying down diaphragm paralysis Temporary paralysis Your diaphragm can Thank you for a very fine explanation of the process! A common symptom of diabetic peripheral neuropathy is numbness. Noninvasive ventilation (such as CPAP or BiPAP), especially at night, Diaphragmatic placation: a surgery in which the diaphragm is "tacked down" with sutures to aid inspiration, Diaphragm pacemakers (if the phrenic nerves are still functional a pacemaker may work well), Mechanical ventilation (oftentimes, a tracheostomy and mechanical ventilation is required), Phrenic nerve reconstruction (a relatively new and very specialized procedure, reconstruction may be effective). Mediastina pleura (thin tissue covering the chest cavity between your lungs). WebWhile Kehr's sign (left shoulder pain) is commonly a symptom of splenic rupture, right shoulder pain typically signals liver or gallbladder irritation. Chest pain- the muscles in the chest get pretty stressed when dealing with labored breathing and esophageal spasms. Diabetic foot pain is often accompanied by tingling and burning in the feet. The nerves that control the movement of the diaphragm away from and towards the lungs as we breathe are known as the phrenic nerves. You may experience shortness of breath and sleep problems. 25th ed. If the phrenic nerve has been damaged, microsurgery is an option. We do not endorse non-Cleveland Clinic products or services. The diaphragm muscle turns off and the patient may have difficulty breathing. The nerve pain gets very intense. WebThe pain from this condition may spread from the buttocks to the back of the leg. Issues with the lungs or diaphragm could be the cause of referred pain in one side of the neck or upper shoulder area. over a year ago. 2014;13(9):924-35. doi:10.1016/S1474-4422(14)70102-4, Gordin E, Lee TS, Ducic Y, Arnaoutakis D. Facial nerve trauma: evaluation and considerations in management. 2015;19(3):65-7. doi:10.1097/NRL.0000000000000008, Parikh V, Kowalski M. Comparison of phrenic nerve injury during atrial fibrillation ablation between different modalities, pathophysiology and management. Nerve Irritation. A new app-based 3-D model of the full female anatomy is said to be the most advanced to date and could help change the level of medical care women. Phrenic nerve injury is usually diagnosed by conducting a physical exam, asking the patient about previous medical treatments that may have affected the neck or chest, and considering whether the patient has severe shortness of breath and is unable to perform simple day-to-day activities. Pain from this condition can travel from the lower back to the leg, and may include pins and needles, numbness, and even weakness in the affected area. In addition, trauma from motor vehicle accidents or falls and chiropractic manipulation can result in injury to the phrenic nerve. This contraction makes it flatter, creating negative pressure in the chest. I have trouble breathing and going up stairs. WebWhat does phrenic nerve control? Learn to take note of what your pain feels like during your everyday life. Thank you, {{form.email}}, for signing up. When one or both phrenic nerves are damaged or severed, the diaphragm can no longer contract, resulting in paresis (partial paralysis) or paralysis. More serious phrenic nerve damage can paralyze the diaphragm and cause difficulty breathing. With phrenic nerve irritation, you might also experience: Your diaphragm can become temporarily paralyzed if youve had the wind knocked out of you from a direct hit to your abdomen. The most common nerve issue that causes left shoulder pain is the Suprascapular nerve. Health-n-joy349544 Therefore, the phrenic nerve and the breathing muscle on the side of the block are paralyzed by an interscalene nerve block. The lungs can still partially function due to rib movements, but this type of breathing is not adequate. You can learn more about how we ensure our content is accurate and current by reading our. In many cases, symptoms improve, especially if caused by a treatable condition. WebWhen the phrenic nerve is injured, the electrical signals in it stop traveling from the brain to the diaphragm muscle. It's also important to treat the underlying cause of the phrenic nerve injury. There are 8 carpal bones, 5 metacarpal bones, and 14 phalanges in your hand and wrist. One of the most common causes is diabetes. Other treatments may be used for chronic nerve pain as well, such as physical therapy or nerve blocks, which are performed by injecting chemicals or anesthetics to the area, or by deliberately cutting or damaging certain parts of the nerve. I am in the process of having these tests set up to do. Verywell Health's content is for informational and educational purposes only. Carl Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education. Neurologist: DOKZOK, replied 2 day ago. It is FREE! He also had to have a heart catheterization to rule out any blockages of his arteries, which came back perfect. Overview of polyneuropathy. Damage to a phrenic nerve can lead to diaphragm weakness or paralysis. Central nervous system causes are possible as well. Hiatal hernia. Ulnar nerve entrapment occurs when the nerve is compressed in the elbow or the hand and wrist. 4th ed. It can be temporary (reversible) or permanent. Peripheral neuropathy treatments. Philadelphia, Pa.: Saunders Elsevier; 2016. https://www.clinicalkey.com. WebThe phrenic nerve can also be damaged from blunt or penetrating trauma[6], metabolic diseases like diabetes[7], infectious causes such as Lyme disease and herpes zoster[8][9], direct invasion by tumor Why does the phrenic nerve referred pain? Cookies collect information about your preferences and your devices and are used to make the site work as you expect it to, to understand how you interact with the site, and to show advertisements that are targeted to your interests. For some people, drinking juice or eating right before a workout can increase the possibility of side stiches. Some even say they can be found in humans. A person with unilateral diaphragm paralysis may not have significant symptoms (with some causes like neuralgic amyotrophy, there may be shoulder pain and arm weakness on their affected side). A nerve graft may be needed to avoid stretching. Every nerve in your peripheral system has a specific function, so symptoms depend on the type of nerves affected. It is like injury happens For others, the pain may be severe and nearly unbearable. A paralyzed diaphragm affects your lungs ability to exchange air. Adv Urol. He went to see his doctor but he had no clue what was wrong with him and he told him to just live with it. The phrenic nerve performs this function multiple times per minute throughout your lifetime. Additionally, nerve pain may be localized (felt at or near the area of nerve damage) or referred (felt somewhere else in the body). The left phrenic nerve passes just anterior to the pericardium (the lining of the heart) near the left ventricle. Accessed March 25, 2019. The human phrenic nerve serves as a morphological conduit for autonomic nerves and innervates the caval body of the diaphragm. Microsurgery. information is beneficial, we may combine your email and website usage information with Goldman L, et al., eds. Signs of this potentially fatal complication. WebWhat does phrenic nerve control? Also discover over 20, If you tend to get hiccups when you're drunk, you might be wondering whether there's something serious going on. For others, symptoms can include a chronic prickling, tingling, About the symptoms well, I am not that sure but I have heard that there are a lot of symptoms, for example from being asymptomatic or respiratory influence. Persistent hiccups can be uncomfortable and annoying. Bilateral diaphragmatic paralysis due to cervical chiropractic manipulation. The phrenic nerves are also the nerves responsible for a very common symptom related to contraction and spasm of the diaphragmhiccups. A lot of people dont know the importance of phrenic nerve. The phrenic nerves play an important role in breathing. https://www.foundationforpn.org/what-is-peripheral-neuropathy/symptoms/. Mine is a result of a motor vehicle accident in which I received a whiplash injury and closed skull injury. All rights reserved. Symptoms of peripheral neuropathy. There are several known causes that can lead to diaphragm paralysis: Birth In: StatPearls. Anesth Analg. Tumors or other structures that press on the phrenic nerve may lead to damage, including:. Except for abdominal bloating he denies any other symptoms. Gray's Anatomy for Students, Churchill Livingstone, 2019.Oliver K., Ashurst, J. StatPearls, "Anatomy, Thorax, Phrenic Nerves," StatPearls Publishing 2021.Pulmonology: "Diaphragmatic dysfunction.". Signs and symptoms of peripheral neuropathy might include: Gradual onset of numbness, prickling or tingling in your feet or hands, which can spread upward into Peripheral neuropathy (adult). The phrenic nerves pass through the diaphragm upon reaching it. Peripheral neuropathy fact sheet. Read our, Neuropathic, Autoimmune, and Infectious Processes, Endotracheal Tube: Purpose, What to Expect, and Risks, The Anatomy of the Superior Laryngeal Nerve, Causes of Collarbone Pain and Treatment Options, A Powerful Straw-Like Device Could Cure Your Hiccups, Cervical spondylosis as a possible hidden reason beyond delayed phrenic nerve distal motor latency, MRI reconstructions of human phrenic nerve anatomy and computational modeling of cryoballoon ablative therapy, Development of the diaphragm a skeletal muscle essential for mammalian respiration, Pancoast's tumour presenting as shoulder pain in an orthopaedic clinic, Phrenic nerve stimulation for central sleep apnea: wiping out apnea or whipping the muscles, The human phrenic nerve serves as a morphological conduit for autonomic nerves and innervates the caval body of the diaphragm, Chronic hiccups: an underestimated problem, Surgical approaches to supradiaphragmatic segment of IVC and right atrium through abdominal cavity during intravenous tumor thrombus removal, Bilateral diaphragmatic paralysis due to cervical chiropractic manipulation, Comparison of phrenic nerve injury during atrial fibrillation ablation between different modalities, pathophysiology and management. Minor irritation of this nerve can cause hiccups. Peripheral neuropathy care at Mayo Clinic. A single copy of these materials may be reprinted for noncommercial personal use only. The diaphragm muscle turns off and the patient may have "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. This finding could have important implications with regard to nerve stimulation practices. Surgery to the neck, chest, or liver can damage the nerve, and cardiac surgery is the most common cause of trauma to the phrenic nerve. Treatment of diabetic neuropathy. The phrenic nerves begin in the neck (cervical spine) and travel to the right and left diaphragm to control contraction and inspiration. Paralysis of the diaphragm is caused by damage to both phrenic nerves. They enter the muscle and innervate it from the lower surface. Read our, Other Symptoms Associated With Nerve Pain, An Overview of Nerve Pain After Abdominal Surgery. Nervous tissue is one of the four types of tissue and is made up of neurons (nerve cells) and supporting cells called neuroglia. As the nerves enter the chest, they take somewhat different paths as they run through the posterior mediastinum (the area between the lungs): It then passes through the vena cava hiatus on its way to the diaphragm. Shortness of breath or difficulty breathing, especially if lying flat requires more pillows behind your head makes it easier to breathe. Nerve pain can arise from a variety of Code of Conduct | HIPAA Notice of Privacy Practices | Patient Bill of Rights | Notice of Email Security Incident | Nondiscrimination & Accessibility Notice | Medicare ACO Public Reporting | Pricing Information | Report a Compliment/Concern | Visitation | Download McLeod Health Mission & Values | Community Health Needs Assessments | Financial Assistance Policy. Phrenic nerve damage after lap chole with adhesions, Paralyzed hemidiaphragm (Right), doctor cut my right phrenic nerve during thyroidectomy, Phrenic nerve damage, can it get worse if I don't have surgery to correct it, High Blood Pressure with COPD exercises with paralyzed diaphragn, what are the symptoms of thorasic spine nerve damage, Left Should Pain/Swollen Left-Side Collar Bone -- Post Gallbladder Removal/Hiatal Hernia Repair, Breast augmentation - post op - nerve damage, Nerve Damage - sub costal nerve damage post laporoscopic surgery of gallbladder removal, Nerve damage post hip replacement surgery, Neck and throat have a shooting pain with I breath in. Pain from this condition can travel from the lower back to the leg, and may include pins and needles, numbness, and even weakness in the affected area. Take breaks when needed if you feel like youre starting to burn out, its okay to take a few days off. It's probably nothing, The latest research shows that your brain is capable of an astounding amount of growth and recovery after an injury. Treasure Island, FL: StatPearls Publishing. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Seek medical care right away if you notice unusual tingling, weakness or pain in your hands or feet. I have phrenic nerve damage from a heart ablasion. There is no function in the right diaphragm. This multi-modal treatment approach can keep nerve pain symptoms under better control. It has been noted that phrenic nerve stimulation for central sleep apnea can cause sympathetic activity (release of catecholamines) that can lead to worsening or even an increased risk of death. 3) Learn to live with it. The phrenic nerve provides the primary motor supply to the diaphragm, the major respiratory muscle. Burning in the feet. Neurologist. Recognizing Amyotrophic Lateral Sclerosis: What Are The Early And Advanced ALS Signs And Symptoms? Consider keeping a pain journalso you have something to reference when talking with your practitioner. Feldman EL, et al. Sciatica could be caused WebFast heart rate, chest pain and tightness or trouble breathing (especially when lying down). Most people describe their chronic nerve pain with a similar set of words. Could this be phrenic nerve damage??? Sci Rep. 2018;8(1):11697. doi:10.1038/s41598-018-30145-x, Kohse EK, Hollmann MW, Bardenheuer HJ, Kessler J. When I brought this 4th option up to my husband's pulmonologist, he had never heard of it, but was willing to call Dr. Kauffman and discuss it with him. With new technologies and imaging equipment, doctors are more prepared than ever to determine the cause of a diaphragm spasm and come up with a positive treatment plan. Since a paralyzed diaphragm results in a paradoxical motion of he diaphragm (the diaphragm moves up in the chest during inspiration and down during expiration), a person's abdomen may be noted to move inward rather than outward with inspiration. Depending on the location of phrenic nerve damage, paralysis may affect one side of your diaphragm (unilateral) or both sides (bilateral). You may notice breathlessness during physical activity, though, or when you are lying down (orthopnea). AskMayoExpert. Procedures like intercostal nerve transfer or phrenic nerve stimulation may then be required to restore diaphragmatic movement. WebHowever, most sources agree that phrenic nerve pain and injury should resolve within a few days to weeks following laparoscopy." Nearly a year ago, my husband began complaining of difficulty taking a deep breath, feeling pressure in the diaphragm area on the right side, particularly after eating. He will focus on yoursevere shortness of breath. What is the outlook for a diaphragm spasm? 2015;8(1):1-13. doi:10.1055/s-0034-1372522, Naja Z, Naja AS, Rajab O, Mugharbil A, Shatila AR, Al hassan J. If you don't feel like your doctor is getting to the bottom of your issues insist they do more testing or refer you on to somebody else. Let's take a closer look. You may opt-out of email communications at any time by clicking on Last reviewed by a Cleveland Clinic medical professional on 01/09/2022. Your nerve sends signals that cause your diaphragm to contract (become thicker and flatter). Regardless of the cause, nerve pain can feel like any of the following: Burning 1 Tingling 1 Shooting Sharp 1 Stabbing Prickling Like other types of pain, nerve In other cases, an underlying condition may need to be addressed, and once the condition is treated, the spasm is treated as well. The phrenic nerve is among the most important nerves in the body due to its role in respiration. I have finally convinced my Doctor to give me a sniff test and others. Sometimes the spasm is short-lived, particularly if it occurs as a result of a sucker punch.. Additionally, you can apply pressure with your hand to the pain point and bend backward and forward slowly. Hiccups Irritation of the phrenic nerve by way of the Vagus nerve. Originating in the cervical spine (C3 to C5), the phrenic nerves are vulnerable to injury as they travel down the neck and through the chest into the diaphragm. Rakel D, ed. The peripheral nerves also send sensory information to the central nervous system. We do yet know the financials of how it will all work, whether insurance will help pay, what the recovery time will be, or any of those details as of yet, but at least we have a hope at this point that we did not have prior. However, in most cases, either at-home treatments or medical treatments can cure the symptoms. Ulnar nerve entrapment occurs when the nerve is compressed in the elbow or the hand and wrist. Learn more about the causes, treatments, and risk, Hiccups can strike your toddler at any time. Policy. "Cleveland Clinic: "Phrenic Nerve. The phrenic nerve regularly stimulates it to contract. These can be broken down by mechanism. Your phrenic nerve also provides touch and pain sensory information to your: Your phrenic nerve connects to the C3 to C5 cervical (neck) nerve roots of your spinal cord. Because the portion of the peritoneum that underlies the diaphragm is innervated by the phrenic nerve, it could explain the shoulder tip pain. WebSummary. It is like injury happens above the third vertebrae. Ali RH, Farouk MM, Moussa SG. For some, it's a stabbing pain in the middle of the night. WebWhat does phrenic nerve pain feel like? Additionally, phrenic nerves can be damaged by: You should consult your doctor if you have trouble breathing at any time. Knowing what effect phrenic nerve stimulation has on sympathetic activity, and the results of that activity could help researchers and physicians better weigh the risks and benefits of these treatments. It is the muscle responsible for helping you breathe. The left phrenic nerve innervates the left Hey guys. After all other possible issues were ruled out, a phrenic nerve conduction study was done and concluded that in fact, the phrenic nerve on his right side was indeed, dead. WebNeuropathy is a medical condition that just means nerve damage. other information we have about you. Sometimes the spasms are due to normal overexertion and can be relieved easily. Patients are often misdiagnosed because the symptoms are similar to those of pneumonia or asthma. WebThe phrenic nerve controls the diaphragm, which is the major muscle for breathing. After doing so, he was actually very excited about this cutting edge treatment option, and equally excited that there is a 4th option to offer his future patients potentially. Plenty of stories abound online providing advice for getting a defined or chiseled jawline. WebWhat does phrenic nerve pain feel like? Lancet Neurol. Its usually performed through a small incision in either your abdomen or chest wall. Treatments for persistent hiccups include: These steps can keep your nervous system healthy: You should call your healthcare provider if you experience: Your phrenic nerves are critical to breathing. Oswald Lind. Sometimes you may be unable to feel your feet while walking. Damage to a phrenic nerve can lead to a paralyzed diaphragm. In addition, scar tissue can form in the neck and compress the nerve. There are a lot of different causes of neuropathy, the most common cause in the United States is diabetes but other C7 nerve pain is a type of neuropathy that is caused by compression or damage to the C7 nerve root in your cervical spine. A significant decrease in lung capacity is noted whether a single or both nerves are damaged, with a decrease of roughly 50% due to one-sided injury and a decrease of 70% to 80% when both nerves are involved. Does chewing gum work? Neuropathic pain. Peripheral neuropathy is nerve damage caused by a number of different conditions. I have a spinal cord stim implant that does take the edge off the pain as long as Im laying down. This content does not have an Arabic version. The information on this site is intended to increase your awareness and understanding of specific health issues and services at McLeod Health. Philadelphia, Pa.: Elsevier; 2018. https://www.clinicalkey.com. Other causes are more involved and may have a number of additional symptoms associated with them. These may include: acupuncture herbal medicine benfotiamine (a form of vitamin B1) supplements alpha-lipoic acid (an antioxidant) supplements Our story is long, but I want to encourage anybody who is going through what we have, to be your own advocate when it comes to your healthcare! It grants freedom from the mechanical ventilator, enables speech, and improves quality of life. C7 nerve pain is a type of neuropathy that is caused by compression or damage to the C7 nerve root in your cervical spine. https://www.foundationforpn.org/what-is-peripheral-neuropathy/causes/. How Can You Keep Your Phrenic Nerves Healthy? WebSummary. Chiou M, et al. She is an associate clinical professor of neurology at Tufts School of Medicine. Cervical spondylosis as a possible hidden reason beyond delayed phrenic nerve distal motor latency. If you have a hiatal hernia, part of your stomach comes up through your diaphragm in the hiatal opening. Feb. 10, 2021. If these aren't successful, you may need mechanical ventilation for the rest of your life. Other possible effects include tiredness, Surgical procedures, tumors and other issues may irritate your phrenic nerve, bringing on persistent hiccups.

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